منابع مشابه
Isolation and Identification of Prostaglandins from Human Seminal Plasma. 18. Prostaglandins and Related Factors.
A depressor substance which stimulates smooth muscle was discovered by Goldblatt and von Euler in extracts of human seminal plasma and of the vesicular glands of sheep (1,Z). The active principle, called prostaglandin, wm shown to have acidic properties. Investigations on its occurrence and biological effects were carried out by von Euler (2) and more recently by El&son (3). Two biologically ac...
متن کاملIsolation of two novel E prostaglandins in human seminal fluid.
cis-8,11,14,17-[1-14C]Eicosatetraenoic acid was incubated with microsomes of ram seminal vesicles and 1 mM glutathione for 3 min at 37 degrees C. The main metabolite was identified as 17,18-dehydroprostaglandin E1 by capillary column gas chromatography-mass spectrometry. Human seminal fluid was analyzed for the presence of 17,18-dehydroprostaglandin E1 and prostaglandin E3. Whereas prostaglandi...
متن کاملFibronectin fragments in human seminal plasma.
The study has revealed the presence of fibronectin (FN) fragments and a lack of intact FN in 72 seminal plasma samples. The FN fragmentation was examined by immunoblotting with a monoclonal antibody specific to the central cellular FN domain and was confirmed with a monoclonal antibody directed to the C-terminal domain of FN. Nine FN fragments between 60 and 200 kDa and five fragments of 60-150...
متن کاملDouble Stranded RNA in Human Seminal Plasma
Recently, human semen was shown to contain cell-free nucleic acids, such as DNA, long single stranded RNA, and small RNAs-miRNA and piRNA. The RNAs have been suggested to have potential biological roles as communication molecules between cells and in the temporal and spatial regulation of gene expression in the male reproductive system. Here we demonstrate that human seminal plasma contains a v...
متن کاملP-79: The Correlation between Nitric Oxide Levels in Seminal Plasma with Human Sperm Parameters
Background: Defective sperm quality is a significant cause of infertility in men. It is known that nitric oxide (NO) is a highly reactive free radical gas which has a dual function, being both a cytotoxic and necessary molecule for normal sperm production. Materials and Methods: To investigate correlation between NO levels with sperm parameters, a case-control study were designed with total of ...
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ژورنال
عنوان ژورنال: Journal of Biological Chemistry
سال: 1966
ISSN: 0021-9258
DOI: 10.1016/s0021-9258(18)96910-3